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Infections
Exposure to viral agents has been explored as a causative factor. Although several specific agents have been named, the most commonly discussed virus is the Coxsackie B4 virus. Researchers have suggested that an autoimmune response to a virus may start or accelerate ß-cell destruction. Other viruses theorized to be associated with the onset of Type 1 are cytomegalovirus, rubella, and mumps. Investigation of a viral-Type 1 connection continues, but it is important to note that most individuals with recently diagnosed Type 1 do not show evidence of a recent viral infection. (3,8,18)
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ß-Cell
