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Thiazolidinediones (Actos, Avandia)
Actos and Avandia work by increasing insulin sensitivity. They lower blood sugar through improvement of target cell response to insulin. Persons on these drugs need baseline liver function testing and should be monitored for any signs of hepatic problems. Patients should also be evaluated for any signs of edema or weight gain since they medications can increase fluid retention. These drugs should be used with caution in people with congestive heart failure or on insulin therapy. (25,28,30,48)
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Intervention
