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Oral Hypoglycemic Agents
When sufficient results cannot be obtained through diet and exercise regimens it may become necessary for Type 2 diabetics to take oral hypoglycemic agents aimed at lowering blood glucose levels (see Table 9).
The four major classifications of oral hypoglycemic agents, are secretagogues (sulfonylurea drugs, meglitinides and D-Phenylalanines) biguanides (Metformin), Thiazolidinediones (Actos and Avandia) and Glucosidase Inhibitors (Precose and Glyset) Secretagogues act by increasing pancreatic production of insulin. Metformin's main action is to reducing glucose production in the liver, the Thiazolidinediones decrease insulin resistance and the Glucosidase Inhibitors delay carbohydrate absorption. (48)
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Intervention
